topPTM:EGFR

Epidermal growth factor receptor

Uniprot/Swiss-prot ID EGFR_HUMAN

Protein name Epidermal growth factor receptor

Gene name Name: EGFR
Synonyms: ERBB, ERBB1, HER1

Organism Homo sapiens (Human).

Taxonomic lineage Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo.

Function Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin.; Isoform 2 may act as an antagonist of EGF action.

PTM S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)
N-linked (Glc...)
N-linked (GlcNAc...)
Phosphoserine
S-nitrosocysteine
Phosphothreonine
Phosphotyrosine
DePhosphotyrosine
N6-acetyllysine

Topology Preview

Localization Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Endosome. Endosome membrane. Note=In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER. Endocytosed upon activation by ligand.; Isoform 2: Secreted.

Gene Ontology(GO) C:basolateral plasma membrane
C:endocytic vesicle
C:endoplasmic reticulum membrane
C:endosome
C:endosome membrane
C:extracellular space
C:Golgi membrane
C:integral to membrane
C:membrane raft
C:nuclear membrane
C:nucleus
C:perinuclear region of cytoplasm
C:Shc-EGFR complex
F:actin filament binding
F:ATP binding
F:double-stranded DNA binding
F:epidermal growth factor-activated receptor activity
F:MAP kinase kinase kinase activity
F:protein heterodimerization activity
F:receptor signaling protein tyrosine kinase activity
P:activation of phospholipase A2 activity by calcium-mediated signaling
P:activation of phospholipase C activity
P:axon guidance
P:cell proliferation
P:cell-cell adhesion
P:cerebral cortex cell migration
P:digestive tract morphogenesis
P:embryonic placenta development
P:fibroblast growth factor receptor signaling pathway
P:hair follicle development
P:innate immune response
P:morphogenesis of an epithelial fold
P:negative regulation of apoptotic process
P:negative regulation of epidermal growth factor receptor signaling pathway
P:negative regulation of protein catabolic process
P:neurotrophin TRK receptor signaling pathway
P:ossification
P:phosphatidylinositol-mediated signaling
P:positive regulation of catenin import into nucleus
P:positive regulation of cell migration
P:positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
P:positive regulation of DNA repair
P:positive regulation of DNA replication
P:positive regulation of epithelial cell proliferation
P:positive regulation of fibroblast proliferation
P:positive regulation of MAP kinase activity
P:positive regulation of nitric oxide biosynthetic process
P:positive regulation of protein kinase B signaling cascade
P:protein autophosphorylation
P:protein insertion into membrane
P:regulation of nitric-oxide synthase activity
P:regulation of peptidyl-tyrosine phosphorylation
P:response to UV-A
P:salivary gland morphogenesis

InterPro IPR000494: EGF_rcpt_L
IPR006211: Furin-like_Cys-rich_dom
IPR006212: Furin_repeat
IPR009030: Growth_fac_rcpt_N_dom
IPR011009: Kinase-like_dom
IPR000719: Prot_kinase_cat_dom
IPR017441: Protein_kinase_ATP_BS
IPR001245: Ser-Thr/Tyr_kinase_cat_dom
IPR008266: Tyr_kinase_AS
IPR020635: Tyr_kinase_cat_dom
IPR016245: Tyr_kinase_EGF/ERB/XmrK_rcpt

PDB

Entry	Method	Å	Chain	Positions	3D
1DNQ	Model	-	A	25-336
1DNR	Model	-	A	337-645
1IVO	X-ray	3.30	A/B	25-646
1M14	X-ray	2.60	A	695-1022
1M17	X-ray	2.60	A	695-1022
1MOX	X-ray	2.50	A/B	25-525
1NQL	X-ray	2.80	A	25-642
1XKK	X-ray	2.40	A	695-1022
1YY9	X-ray	2.60	A	25-642
1Z9I	NMR	-	A	669-721
2EB2	X-ray	2.50	A	695-1022
2EB3	X-ray	2.84	A	695-1022
2EXP	Model	-	A	311-326
2EXQ	Model	-	A	27-536
2GS2	X-ray	2.80	A	696-1022
2GS6	X-ray	2.60	A	696-1022
2GS7	X-ray	2.60	A/B	696-1022
2ITN	X-ray	2.47	A	696-1019
2ITO	X-ray	3.25	A	696-1022
2ITP	X-ray	2.74	A	696-1022
2ITQ	X-ray	2.68	A	696-1022
2ITT	X-ray	2.73	A	696-1022
2ITU	X-ray	2.80	A	696-1022
2ITV	X-ray	2.47	A	696-1022
2ITW	X-ray	2.88	A	696-1022
2ITX	X-ray	2.98	A	696-1022
2ITY	X-ray	3.42	A	696-1022
2ITZ	X-ray	2.72	A	696-1022
2J5E	X-ray	3.10	A	696-1022
2J5F	X-ray	3.00	A	696-1022
2J6M	X-ray	3.10	A	696-1022
2JIT	X-ray	3.10	A/B	696-1022
2JIU	X-ray	3.05	A/B	695-1022
2JIV	X-ray	3.50	A/B	695-1022
2KS1	NMR	-	B	634-677
2M20	NMR	-	A/B	642-697
2RF9	X-ray	3.50	A/B	696-1022
2RFD	X-ray	3.60	A/B	702-1022
2RFE	X-ray	2.90	A/B/C/D	702-1022
2RGP	X-ray	2.00	A	702-1016
3B2U	X-ray	2.58	A/B/E/I/M/P/S/V	335-538
3B2V	X-ray	3.30	A	25-642
3BEL	X-ray	2.30	A	702-1016
3BUO	X-ray	2.60	A/C	1063-1075
3C09	X-ray	3.20	A/D	335-538
3G5V	X-ray	2.00	C	311-326
3G5Y	X-ray	1.59	E	311-326
3GOP	X-ray	2.80	A	669-1022
3GT8	X-ray	2.96	A/B/C/D	696-1022
3IKA	X-ray	2.90	A/B	694-1022
3LZB	X-ray	2.70	A/B/C/D/E/F/G/H	696-983
3NJP	X-ray	3.30	A/B	25-638
3OB2	X-ray	2.10	A	1063-1074
3OP0	X-ray	2.52	C/D	1066-1076
3P0Y	X-ray	1.80	A	334-538
3PFV	X-ray	2.27	C/D	1066-1076
3POZ	X-ray	1.50	A	696-1022
3QWQ	X-ray	2.75	A	1-642
3UG1	X-ray	2.75	A	695-1022
3UG2	X-ray	2.50	A	695-1022
3VJN	X-ray	2.34	A	695-1022
3VJO	X-ray	2.64	A	695-1022
3VRP	X-ray	1.52	B	1062-1074
3VRR	X-ray	2.00	C	1062-1074
3W2O	X-ray	2.35	A	698-1022
3W2P	X-ray	2.05	A	698-1022
3W2Q	X-ray	2.20	A	698-1022
3W2R	X-ray	2.05	A	698-1022
3W2S	X-ray	1.90	A	696-1022
3W32	X-ray	1.80	A	696-1022
3W33	X-ray	1.70	A	696-1022
4G5J	X-ray	2.80	A	696-1022
4G5P	X-ray	3.17	A/B	696-1022
4HJO	X-ray	2.75	A	696-1022
4I1Z	X-ray	3.00	A	695-1022
4I20	X-ray	3.34	A	695-1022
4I21	X-ray	3.37	A/B	695-1022
4I22	X-ray	1.71	A	695-1022
4I23	X-ray	2.80	A	695-1022
4I24	X-ray	1.80	A/B	695-1022

Sequence

Length: 1210

MRPSGTAGAA LLALLAALCP ASRALEEKKV CQGTSNKLTQ LGTFEDHFLS LQRMFNNCEV VLGNLEITYV QRNYDLSFLK TIQEVAGYVL IALNTVERIP LENLQIIRGN MYYENSYALA VLSNYDANKT GLKELPMRNL QEILHGAVRF SNNPALCNVE SIQWRDIVSS DFLSNMSMDF QNHLGSCQKC DPSCPNGSCW GAGEENCQKL TKIICAQQCS GRCRGKSPSD CCHNQCAAGC TGPRESDCLV CRKFRDEATC KDTCPPLMLY NPTTYQMDVN PEGKYSFGAT CVKKCPRNYV VTDHGSCVRA CGADSYEMEE DGVRKCKKCE GPCRKVCNGI GIGEFKDSLS INATNIKHFK NCTSISGDLH ILPVAFRGDS FTHTPPLDPQ ELDILKTVKE ITGFLLIQAW PENRTDLHAF ENLEIIRGRT KQHGQFSLAV VSLNITSLGL RSLKEISDGD VIISGNKNLC YANTINWKKL FGTSGQKTKI ISNRGENSCK ATGQVCHALC SPEGCWGPEP RDCVSCRNVS RGRECVDKCN LLEGEPREFV ENSECIQCHP ECLPQAMNIT CTGRGPDNCI QCAHYIDGPH CVKTCPAGVM GENNTLVWKY ADAGHVCHLC HPNCTYGCTG PGLEGCPTNG PKIPSIATGM VGALLLLLVV ALGIGLFMRR RHIVRKRTLR RLLQERELVE PLTPSGEAPN QALLRILKET EFKKIKVLGS GAFGTVYKGL WIPEGEKVKI PVAIKELREA TSPKANKEIL DEAYVMASVD NPHVCRLLGI CLTSTVQLIT QLMPFGCLLD YVREHKDNIG SQYLLNWCVQ IAKGMNYLED RRLVHRDLAA RNVLVKTPQH VKITDFGLAK LLGAEEKEYH AEGGKVPIKW MALESILHRI YTHQSDVWSY GVTVWELMTF GSKPYDGIPA SEISSILEKG ERLPQPPICT IDVYMIMVKC WMIDADSRPK FRELIIEFSK MARDPQRYLV IQGDERMHLP SPTDSNFYRA LMDEEDMDDV VDADEYLIPQ QGFFSSPSTS RTPLLSSLSA TSNNSTVACI DRNGLQSCPI KEDSFLQRYS SDPTGALTED SIDDTFLPVP EYINQSVPKR PAGSVQNPVY HNQPLNPAPS RDPHYQDPHS TAVGNPEYLN TVQPTCVNST FDSPAHWAQK GSHQISLDNP DYQQDFFPKE AKPNGIFKGS TAENAEYLRV APQSSEFIGA

Kegg Pathway hsa04010:MAPK signaling pathway - Homo sapiens (human)
hsa04012:ErbB signaling pathway - Homo sapiens (human)
hsa04020:Calcium signaling pathway - Homo sapiens (human)
hsa04060:Cytokine-cytokine receptor interaction - Homo sapiens (human)
hsa04066:HIF-1 signaling pathway - Homo sapiens (human)
hsa04144:Endocytosis - Homo sapiens (human)
hsa04151:PI3K-Akt signaling pathway - Homo sapiens (human)
hsa04320:Dorso-ventral axis formation - Homo sapiens (human)
hsa04510:Focal adhesion - Homo sapiens (human)
hsa04520:Adherens junction - Homo sapiens (human)
hsa04540:Gap junction - Homo sapiens (human)
hsa04810:Regulation of actin cytoskeleton - Homo sapiens (human)
hsa04912:GnRH signaling pathway - Homo sapiens (human)
hsa04915:Estrogen signaling pathway - Homo sapiens (human)
hsa05120:Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
hsa05160:Hepatitis C - Homo sapiens (human)
hsa05200:Pathways in cancer - Homo sapiens (human)
hsa05205:Proteoglycans in cancer - Homo sapiens (human)
hsa05212:Pancreatic cancer - Homo sapiens (human)
hsa05213:Endometrial cancer - Homo sapiens (human)
hsa05214:Glioma - Homo sapiens (human)
hsa05215:Prostate cancer - Homo sapiens (human)
hsa05218:Melanoma - Homo sapiens (human)
hsa05219:Bladder cancer - Homo sapiens (human)
hsa05223:Non-small cell lung cancer - Homo sapiens (human)

Disease Reference

KEGG disease	H00016: Oral cancer H00017: Esophageal cancer H00018: Gastric cancer H00022: Bladder cancer H00028: Choriocarcinoma H00030: Cervical cancer H00042: Glioma H00055: Laryngeal cancer
Omim	131550: EPIDERMAL GROWTH FACTOR RECEPTOR; EGFR ;;V-ERB-B AVIAN ERYTHROBLASTIC LEUKEMIA VIRAL ONCOGEN 211980: LUNG CANCER ALVEOLAR CELL CARCINOMA, INCLUDED;; ADENOCARCINOMA OF LUNG, INCLUDED;; NONSMALL

Drug Reference

Kegg drug

D01977: Gefitinib (JAN/USAN/INN); Iressa (TN)
D03350: Canertinib dihydrochloride (USAN)
D03455: Cetuximab (genetical recombination) (JAN); Cetuximab (USAN/INN); Erbitux (TN)
D04023: Erlotinib hydrochloride (JAN/USAN); Tarceva (TN)
D04024: Lapatinib tosilate hydrate (JAN); Lapatinib ditosylate (USAN); Tykerb (TN)
D05350: Panitumumab (genetical recombination) (JAN); Panitumumab (USAN/INN); Vectibix (TN)
D05399: Pelitinib (USAN/INN)
D06407: Vandetanib (JAN/USAN/INN); Caprelsa (TN)
D07907: Erlotinib (INN); Tarceva (TN)
D08108: Lapatinib (INN)
D08950: Neratinib (INN/USAN)
D09689: Varlitinib (USAN/INN)
D09690: Varlitinib tosylate (USAN)
D09724: Afatinib (USAN/INN)
D09733: Afatinib maleate (JAN); Afatinib dimaleate (USAN)
D09883: Dacomitinib (USAN/INN)
D10018: Necitumumab (USAN/INN)
D10031: Zalutumumab (USAN/INN)
D10439: Imgatuzumab (USAN/INN)

DrugBank

DB00002: Cetuximab
DB00530: Erlotinib
DB00317: Gefitinib
DB01259: Lapatinib
DB00281: Lidocaine
DB01269: Panitumumab
DB00072: Trastuzumab

Start	Sequence	End	Region	Literature
25	LEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPS	645	Extracellular	Potential
646	`IATGMVGALLLLLVVALGIGLFM`	668	Transmembrane(Helical)	Potential
669	RRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1210	Cytoplasmic	Potential

PTM	Site	Enzyme	Literature	Resource	View 3D
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	31	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (Glc...)	56	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (GlcNAc...)	56	-		Uniprot	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	58	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (GlcNAc...)	73	-		Uniprot	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (Glc...)	128	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (GlcNAc...)	128	-		Uniprot	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
Phosphoserine	151	-		Phosphositeplus	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	157	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (Glc...)	175	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (GlcNAc...)	175	-		Uniprot	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	187	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	190	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-nitrosocysteine	190	-		dbSNO	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	194	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (Glc...)	196	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (GlcNAc...)	196	-		Uniprot	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	199	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	207	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	215	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	219	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	223	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
Phosphoserine	229	-		Phosphositeplus / Uniprot	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	231	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	232	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	236	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	240	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	248	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	251	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	260	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	264	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
Phosphothreonine	290	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	291	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-nitrosocysteine	291	-		dbSNO	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	295	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	307	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	311	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXP_A; 2EXQ_A; 3B2V_A; 3G5V_C; 3G5Y_E; 3NJP_A/B; 3QWQ_A;
S-nitrosocysteine	311	-		dbSNO	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXP_A; 2EXQ_A; 3B2V_A; 3G5V_C; 3G5Y_E; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	326	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXP_A; 2EXQ_A; 3B2V_A; 3G5V_C; 3G5Y_E; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	329	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-nitrosocysteine	329	-		dbSNO	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	333	-		HPRD	1DNQ_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	337	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
N-linked (Glc...)	352	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
N-linked (GlcNAc...)	352	-		Uniprot	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
N-linked (Glc...)	361	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
N-linked (GlcNAc...)	361	-		Uniprot	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	362	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
N-linked (Glc...)	413	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
N-linked (GlcNAc...)	413	-		Uniprot	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
N-linked (Glc...)	444	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
N-linked (GlcNAc...)	444	-		Uniprot	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	470	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
S-nitrosocysteine	470	-		dbSNO	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	499	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	506	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	510	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
Phosphoserine	511	-		Phosphositeplus	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	515	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	523	-		HPRD	1DNR_A; 1IVO_A/B; 1MOX_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	526	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
N-linked (Glc...)	528	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
N-linked (GlcNAc...)	528	-		Uniprot	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	535	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 2EXQ_A; 3B2U_A/B/E/I/M/P/S/V; 3B2V_A; 3C09_A/D; 3NJP_A/B; 3P0Y_A; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	539	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	555	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	558	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	562	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (Glc...)	568	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (GlcNAc...)	568	-		Uniprot	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	571	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	579	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	582	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
Phosphotyrosine	585	-		Phosphositeplus	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	591	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	595	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (Glc...)	603	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (GlcNAc...)	603	-		Uniprot	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	617	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	620	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
N-linked (Glc...)	623	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	624	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	628	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 3B2V_A; 3NJP_A/B; 3QWQ_A;
S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)	636	-		HPRD	1DNR_A; 1IVO_A/B; 1NQL_A; 1YY9_A; 2KS1_B; 3B2V_A; 3NJP_A/B; 3QWQ_A;
Phosphothreonine	678	PRKCD		HPRD / Phosphositeplus / Uniprot / PhosphoELM	1Z9I_A; 2M20_A/B; 3GOP_A;
Phosphothreonine	693	-		HPRD / HPRD / Phosphositeplus / SysPTM / Uniprot / PhosphoELM	1Z9I_A; 2M20_A/B; 3GOP_A;
Phosphoserine	695	-		HPRD / PhosphoELM / Phosphositeplus / SysPTM / Uniprot	1M14_A; 1M17_A; 1XKK_A; 1Z9I_A; 2EB2_A; 2EB3_A; 2JIU_A/B; 2JIV_A/B; 2M20_A/B; 3GOP_A; 3IKA_A/B; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphoserine	720	-		HPRD	1M14_A; 1M17_A; 1XKK_A; 1Z9I_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphothreonine	725	-		HPRD / SysPTM	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphotyrosine	727	-		HPRD / Phosphositeplus	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphoserine	752	-		Phosphositeplus	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphotyrosine	764	-		Phosphositeplus	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphoserine	768	CAMK2A		HPRD / Phosphositeplus / PhosphoELM	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphotyrosine	827	-		Phosphositeplus	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphotyrosine	869	SRC		HPRD / Phosphositeplus / SysPTM / PhosphoELM	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphotyrosine	891	-		HPRD	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphotyrosine	915	SRC		HPRD / PhosphoELM	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphotyrosine	944	SRC		HPRD / Phosphositeplus / PhosphoELM	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphotyrosine	978	-		HPRD / PhosphoELM / Phosphositeplus	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3LZB_A/B/C/D/E/F/G/H; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphoserine	991	-		HPRD / PhosphoELM / Phosphositeplus / SysPTM / Uniprot	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphothreonine	993	-		HPRD / PhosphoELM / Phosphositeplus / SysPTM	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphoserine	995	-		HPRD / PhosphoELM / Phosphositeplus / SysPTM / Uniprot	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphotyrosine	998	SRC		HPRD / PhosphoELM / Phosphositeplus / SysPTM / Uniprot	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
DePhosphotyrosine	1016	-		HPRD	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphotyrosine	1016	-		HPRD / HPRD / Phosphositeplus / Uniprot / PhosphoELM	1M14_A; 1M17_A; 1XKK_A; 2EB2_A; 2EB3_A; 2GS2_A; 2GS6_A; 2GS7_A/B; 2ITN_A; 2ITO_A; 2ITP_A; 2ITQ_A; 2ITT_A; 2ITU_A; 2ITV_A; 2ITW_A; 2ITX_A; 2ITY_A; 2ITZ_A; 2J5E_A; 2J5F_A; 2J6M_A; 2JIT_A/B; 2JIU_A/B; 2JIV_A/B; 2RF9_A/B; 2RFD_A/B; 2RFE_A/B/C/D; 2RGP_A; 3BEL_A; 3GOP_A; 3GT8_A/B/C/D; 3IKA_A/B; 3POZ_A; 3UG1_A; 3UG2_A; 3VJN_A; 3VJO_A; 3W2O_A; 3W2P_A; 3W2Q_A; 3W2R_A; 3W2S_A; 3W32_A; 3W33_A; 4G5J_A; 4G5P_A/B; 4HJO_A; 4I1Z_A; 4I20_A; 4I21_A/B; 4I22_A; 4I23_A; 4I24_A/B;
Phosphoserine	1025	-		HPRD / PhosphoELM / Phosphositeplus / SysPTM
Phosphoserine	1026	-		HPRD / Phosphositeplus / SysPTM / Uniprot / PhosphoELM
Phosphoserine	1028	-		HPRD / PhosphoELM
Phosphoserine	1030	-		Phosphositeplus
Phosphoserine	1036	-		HPRD / SysPTM
Phosphoserine	1037	-		HPRD / PhosphoELM / Phosphositeplus / SysPTM
Phosphoserine	1039	-		HPRD / PhosphoELM / Phosphositeplus / SysPTM / Uniprot
Phosphothreonine	1041	-		HPRD / PhosphoELM / Phosphositeplus / SysPTM / Uniprot
Phosphoserine	1042	-		HPRD / PhosphoELM / Phosphositeplus / SysPTM / Uniprot
Phosphoserine	1045	-		HPRD / PhosphoELM / Phosphositeplus / SysPTM
Phosphothreonine	1046	-		Phosphositeplus
Phosphoserine	1057	-		Phosphositeplus
Phosphoserine	1064	CAMK2A		HPRD / PhosphoELM / Phosphositeplus / SysPTM / Uniprot	3BUO_A/C; 3OB2_A; 3VRP_B; 3VRR_C;
Phosphotyrosine	1069	-		HPRD / HPRD / HPRD / HPRD / PhosphoELM / Phosphositeplus / SysPTM	3BUO_A/C; 3OB2_A; 3OP0_C/D; 3PFV_C/D; 3VRP_B; 3VRR_C;
Phosphoserine	1070	CAMK2A		HPRD / HPRD / Phosphositeplus / Uniprot / PhosphoELM	3BUO_A/C; 3OB2_A; 3OP0_C/D; 3PFV_C/D; 3VRP_B; 3VRR_C;
Phosphoserine	1071	CAMK2A		HPRD / HPRD / Phosphositeplus / Uniprot / PhosphoELM	3BUO_A/C; 3OB2_A; 3OP0_C/D; 3PFV_C/D; 3VRP_B; 3VRR_C;
Phosphothreonine	1074	-		Phosphositeplus	3BUO_A/C; 3OB2_A; 3OP0_C/D; 3PFV_C/D; 3VRP_B; 3VRR_C;
Phosphothreonine	1078	-		HPRD / PhosphoELM
Phosphoserine	1081	CAMK2A		HPRD / Phosphositeplus / SysPTM / Uniprot / PhosphoELM
Phosphothreonine	1085	-		HPRD / PhosphoELM / Phosphositeplus
Phosphotyrosine	1092	EGFR		HPRD / HPRD / Phosphositeplus / SysPTM / Uniprot / PhosphoELM
Phosphoserine	1096	-		Phosphositeplus
Phosphoserine	1104	-		PhosphoELM / Phosphositeplus
Phosphotyrosine	1110	EGFR		HPRD / Phosphositeplus / SysPTM / Uniprot / PhosphoELM
Phosphoserine	1120	CAMK2A		HPRD
Phosphotyrosine	1125	SRC		HPRD / Phosphositeplus / PhosphoELM
Phosphotyrosine	1138	-		HPRD / Phosphositeplus / SysPTM
Phosphoserine	1162	-		Phosphositeplus
Phosphoserine	1166	CAMK2A		HPRD / Phosphositeplus / SysPTM / Uniprot / PhosphoELM
Phosphotyrosine	1172	EGFR		HPRD / Phosphositeplus / SysPTM / Uniprot / PhosphoELM
N6-acetyllysine	1179	-		Phosphositeplus
N6-acetyllysine	1182	-		Phosphositeplus
N6-acetyllysine	1188	-		Phosphositeplus
Phosphoserine	1190	-		PhosphoELM / Phosphositeplus
Phosphothreonine	1191	-		Phosphositeplus
DePhosphotyrosine	1197	-		HPRD
Phosphotyrosine	1197	EGFR		HPRD / Phosphositeplus / SysPTM / Uniprot / PhosphoELM
Omega-N-methylated arginine	1199	-		Uniprot